Johns Hopkins All Children's Research

Our Leadership

George Jallo, M.D.

George Jallo, M.D. Interim Vice Dean and Physician-in-Chief

Dr. Jallo is medical director of the Johns Hopkins All Children's Hospital Institute for Brain Protection Sciences (IBPS) and chief of pediatric neurosurgery. He became interim physician-in-chief for the hospital and interim vice dean for the Johns Hopkins University School of Medicine in 2018. An internationally respected pediatric neurosurgeon, Dr. Jallo is a professor of neurosurgery, pediatrics and oncology in the School of Medicine.

Dr. Jallo joined the Johns Hopkins faculty in 2003, was named clinical director of pediatric neurosurgery at The Johns Hopkins Hospital in 2004, and then succeeded Benjamin Carson, M.D., as head of the Division of Pediatric Neurosurgery in 2013. He moved to Johns Hopkins All Children’s in 2015 to start the Institute for Brain Protection Sciences, a multidisciplinary institute that unites clinicians, researchers and educators in a comprehensive program to promote optimal neurodevelopment early in life and provide expert care for children with injuries or illness that can affect the brain.

Dr. Jallo’s areas of expertise include tumors of the brain and spinal cord, intraoperative neurophysiological monitoring for eloquent tumors, use of minimally invasive technologies such as endoscopy and keyhole surgery, and surgical treatment of epilepsy. He has published more than 225 peer-reviewed scientific articles, 69 book chapters and is co-editor of five textbooks on pediatric neurosurgery, pediatric epilepsy surgery and neuroendoscopy.

Dr. Jallo earned his medical degree at the University of Virginia Medical School and completed his residency in neurosurgery at New York University Medical Center and fellowship in pediatric neurosurgery at Beth Israel Medical Center, Institute for Neurology and Neurosurgery, in New York.

Neil Goldenberg, M.D., Ph.D.

Neil Goldenberg, M.D., Ph.D. Clinical and Translational Research Organization Director

Dr. Goldenberg was named director of research at Johns Hopkins All Children's Hospital in July 2012 as well as chief research officer of the All Children's Research Institute and director of the new Clinical and Translational Research Organization at Johns Hopkins All Children's Hospital. He is a professor of pediatrics and medicine at the Johns Hopkins University School of Medicine, and an international leader in the field of venous thromboembolism in children and young adults.

Dr. Goldenberg is overall principal investigator for the National Institutes of Health (NIH)-sponsored Kids-DOTT trial, a multinational randomized controlled trial investigating the optimal duration of anticoagulation (anti-clotting medication) for venous thromboembolism (blood clots in the veins) in patients under 21 years of age. He also serves as principal investigator for two large Hopkins pediatric precision medicine studies being conducted at Johns Hopkins All Children’s Hospital (JHACH, St. Petersburg, FL) and the Johns Hopkins Children’s Center and Bayview campuses (Baltimore, MD): iPICS (Institution-wide Prospective Inception Cohort Study of Individuals with Childhood-Onset Acute and Chronic Health Conditions) and the PREDICT birth cohort study (Prospective Research on Early Determinants of Illness and Children's Health Trajectories). The key aims of these longitudinal cohort studies with parallel biobanking are to discover early determinants of disease incidence and disease outcomes and to develop predictive models involving clinical, genetic, epigenetic, and social/environmental factors that will lead to earlier diagnosis and improved treatments in the future.

In addition to these study leadership roles, Dr. Goldenberg chairs or serves as a member of steering committees and data and safety monitoring committees for several NIH- and pharmaceutical industry-sponsored multicenter clinical trials, and has co-authored numerous international clinical and clinical research guidelines in pediatric thrombosis and stroke. He directs the Johns Hopkins Pediatric Thrombosis Program spanning the FL and MD campuses, and also directs the Pediatric Stroke Program at JHACH.

Dr. Goldenberg has authored over 120 original research reports, review articles, and book chapters, mostly as first or senior author. He is also the co-editor of a definitive textbook from Cambridge University Press on pediatric thrombotic disorders.

Prior to joining Hopkins, Dr. Goldenberg was on the faculty of the University of Colorado School of Medicine and served as director of the Children's Clinical Research Organization and co-director of the pediatric thrombosis and stroke programs at Children's Hospital Colorado. He also directed the Department of Clinical Science and Safety at CPC Clinical Research, a university-affiliated Academic Research Organization that runs NIH- and pharma-sponsored clinical trials. Dr. Goldenberg holds a Ph.D. in Clinical Investigation from the University of Colorado.

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Timothy Osborne, Ph.D.

Timothy Osborne, Ph.D. Director of the Johns Hopkins All Children's Institute for Fundamental Biomedical Research

Dr. Osborne is director of the Johns Hopkins All Children's Institute for Fundamental Biomedical Research and a professor of medicine in the Division of Endocrinology, Diabetes and Metabolism of the Johns Hopkins University School of Medicine.

The institute focuses on basic science and supports and collaborates with researchers in other institutes, departments and centers throughout Johns Hopkins Medicine. Dr. Osborne studies the regulation of cholesterol and fatty-acid metabolism and how that impacts physiology and cell biology with a focus on Sterol Regulatory Element Binding Proteins (SREBPs). His research suggests SREBPs are key to understanding cell-environment interactions such as nutrient sensing and responses to organic and biological threats. Dr. Osborne also is part of a National Institutes of Health-funded study into why some people gain fat in the abdomen and others in the thigh area and what impact that has on their cardiovascular health.

Born in Ouray, Colorado, Dr. Osborne studied fundamental biochemistry and molecular biology at the University of California, Santa Barbara and then earned his Ph.D. in microbiology and molecular biology at UCLA. He did a post-doctoral fellowship at the University of Texas Southwestern Medical Center and then became an assistant professor there, working in the lab of Michael Brown and Joseph Goldstein, who won the 1985 Nobel Prize in Physiology or Medicine “for their discoveries concerning the regulation of cholesterol metabolism.” Dr. Osborne spent 20 years at UC Irvine, working his way up to full professor and chairman of the Department of Molecular Biology and Biochemistry. He most recently worked for the Sanford Burnham Prebys Medical Research Institute in Lake Nona, Florida, as a professor and program director and ultimately scientific director.

Sylvia Powell, M.B.A.

Sylvia Powell, M.B.A. Associate Dean for Administration, Office of the Vice Dean for Johns Hopkins All Children’s Hospital

Sylvia Powell joined The Johns Hopkins University School of Medicine as Assistant Dean for Administration in the Office of the Vice Dean of Education in July 2011. Drawing on more than 35 years of administrative experience in academic medicine, Powell is helping to lead academic growth at Johns Hopkins All Children's Hospital. Based in St. Petersburg, she provides administrative oversight of the development and growth of clinical, translational and basic research programs, including the CTRO and a new biorepository. She is also responsible for academic affairs, including faculty development, fellowships, and the Johns Hopkins All Children's pediatric residency program.

During more than 30 years at the University of Miami School of Medicine, Powell held several administrative roles. She was Vice Chair of Administration for the Department of Neurology and previously served in other positions that focused on academic affairs, research administration, professional services and contracting. Powell holds an M.B.A. from the University of Miami.

From 2008-2011, Powell was Director of Administration for the Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles, part of the Keck School of Medicine at the University of Southern California. In this role she was responsible for all research, philanthropic, professional practice and service line operations of the Children's Center, overseeing a $119 million budget.