Johns Hopkins All Children's Hospital

Pediatric Thrombosis

Venous and arterial thrombosis (blood clots in the veins and arteries) in children are treated with care at the Johns Hopkins All Children’s Cancer & Blood Disorders Institute.

The Thrombosis Program at Johns Hopkins All Children's Hospital in St. Petersburg, Florida, helps children who have developed or are at risk for developing a blood clot in their veins or arteries. The program extends from inpatient to outpatient care, consultation, and access to the latest research developments in treatment through leadership and participation in clinical trials.

Reports indicate that the rate of thrombosis in children has dramatically increased in recent years. While blood clots are less common in children than adults, the consequences are especially important in the young patient whose body is still developing.

The multidisciplinary thrombosis team is focused on treating infants, children and young adults who have developed a blood clot. The program can also provide a thrombophilia evaluation and anticipatory guidance for those children who may be at risk for developing young-onset blood clots as a result of a family history of blood clots or stroke before age of 50.

Our pediatric thrombosis doctors are internationally recognized as leaders in research and management of the pediatric thrombosis patient. They have devoted their careers to caring for these children and are committed to providing the best possible outcomes for their patients.

Conditions We Treat

  • Deep vein thrombosis and/or pulmonary embolism
  • Cerebral sinovenous thrombosis
  • Renal vein thrombosis or hepatic vein thrombosis
  • Paget-Schroetter syndrome / Venous thoracic outlet syndrome
  • May-Thurner syndrome / Iliac vein compression syndrome
  • Antiphospholipid antibody syndrome
  • Factor V Leiden, Prothrombin (Factor II) and other gene variants

Services We Provide

  • Hematological evaluation
  • Thrombophilia testing and interpretation
  • Radiologic evaluation and interpretation
  • Antithrombotic medication prescription and monitoring
  • Thrombolytic therapies
  • Chronic venous insufficiency evaluation
  • Preventive medicine
  • Patient and family education
  • Local, national, and international research and clinical trials

Hear from Dr. Neil Goldenberg, M.D., Ph.D, medical director of our Pediatric
Thrombosis Program:

Neil Goldenberg, M.D., Ph.D., became interested in blood disorders and clotting as a medical student. As director of the thrombosis program and director of research at Johns Hopkins All Children’s Hospital, he dedicates research efforts to better understanding blood clots and how they affect children.


Neil Goldenberg, M.D., Ph.D., director of the thrombosis program and director of research at Johns Hopkins All Children’s Hospital, presents an overview of venous thromboembolism in children and young adults in a Centers for Disease Control and Prevention webinar. 

Read inspiring stories about our Thrombosis patients and program:

JAMA Publishes Practice-Changing Findings of JHACH-Led, NIH-Funded, Randomized Clinical Trial

This landmark trial, led by Neil Goldenberg, M.D., Ph.D., associate dean for research, and the Clinical Coordinating Center team in the Johns Hopkins All Children’s Institute for Clinical and Translational Research, focused on the emerging pediatric challenge of venous thromboembolism (VTE—also known as “blood clots,” including deep vein thrombosis (DVT) and pulmonary embolism (PE)).

Read More

NIH-Sponsored Multinational Trial Led by Johns Hopkins Faculty Member at Johns Hopkins All Children’s Successfully Completes Enrollment

The Johns Hopkins All Children’s Hospital-led Kids-DOTT recently completed patient enrollment, marking another milestone in the landmark randomized clinical trial.

Read More

Have Mentor, Will Travel 

Faculty hematologist at Children’s Hospital of Orange County receives a grant to train with Johns Hopkins All Children’s research director.  

Read More

Deep Vein Thrombosis: A Family's Story

It all started when Janet’s brother-in-law had knee surgery and formed a clot in his calf. After learning from a relative that some in the family had a Protein C Deficiency, a disorder that increases the risk of developing abnormal blood clots, Janet’s husband and three kids got tested. All tested positive for the deficiency. The family’s pediatrician referred the family to Neil A. Goldenberg, M.D., Ph.D., hematologist and director of research at Johns Hopkins All Children’s Hospital...

Read More

World Thrombosis Day: Kids Like Valen Get Clots Too

Valen Roa’s family is getting ready to celebrate his first birthday this week with friends and family, plus a pumpkin as a sign of autumn fun.

Read More

Questions? Give us a call

We know that you want the best possible care for your child. Our team is happy to assist you with your questions and scheduling an appointment.

Meet Our Team

Our pediatric thrombosis doctors are internationally recognized as leaders in research and management of the pediatric thrombosis patient.