Cancer and Blood Disorder Institute

Pediatric Blood & Bone Marrow Transplant (BMT) Program

For blood and bone marrow transplants, you can trust Florida’s largest program at the Johns Hopkins All Children’s Cancer & Blood Disorders Institute.

The Johns Hopkins All Children’s Cancer & Blood Disorders Institute is Florida’s largest pediatric blood and bone marrow transplantation program. Our program has excellent outcomes for children who need bone marrow (stem cell) transplants to treat leukemia, lymphoma, immunodeficiency syndromes and other forms of cancer and blood diseases.

Our program was one of the first pediatric centers in the United States to offer “reduced intensity” transplants in an effort to minimize the toxic effects of radiation and chemotherapy. We perform about 30 hematopoietic stem cell transplants each year.

Pediatric Blood and Marrow Transplant Services

Our program provides a full range of blood and marrow transplant services, including:

  • Bone marrow transplants
  • Peripheral blood stem cell transplants
  • Cord blood transplants

Pediatric Bone Marrow Transplant: 50 Percent Match

Finding a perfect bone marrow match for every child is not always possible. That’s why Johns Hopkins Medicine developed a new treatment for children unable to receive a typical 100 percent match transplant. Johns Hopkins All Children’s has adopted the haploidentical bone marrow transplant protocol, which allows for a 50 percent match. Children who were once without options can now survive.

National and International Protocols

Our program gives our patients access to national and international protocols through our membership, including:

  • National Marrow Donor Program
  • Pediatric Blood and Marrow Transplant Consortium
  • Children’s Oncology Group
  • Center for International Blood and Marrow Transplant Research

Watch and be inspired by Emilie's story:


Three-year-old Emilie was only 9 months old when she was diagnosed with a form of leukemia that can be difficult to treat. But with quality care from Johns Hopkins All Children’s Bone Marrow Transplant Team and a special life-saving gift from her dad, Emilie is thriving today.

Pediatric Clinical Trials

Patients who receive a blood or bone marrow transplant at Johns Hopkins All Children’s may be asked to participate in a clinical trial. A clinical trial is a research study that is designed to help determine the best treatment for a patient with a given disease. These trials help us further our understanding of treatments and diseases, helping us improve care for children with cancer and blood disorders.

Participating in a clinical trial is optional, but may benefit children with similar conditions. If the patient or the patient’s parent choose to participate, the doctor and the consent document will provide detailed information on the treatment and its potential risks and benefits.

Learn more about our clinical trials.

Affiliation with H. Lee Moffitt Cancer Center

Johns Hopkins All Children’s is the only pediatric affiliate of the H. Lee Moffitt Cancer Center. This formal collaboration enables us develop new and innovative therapies for our patients, including leading-edge stem cell transplants. The team works collaboratively with colleagues at Moffitt Cancer Center, sharing their accreditation with the Foundation for Accreditation of Cellular Therapies.

Physicians and researchers at Johns Hopkins All Children’s and the Moffitt Cancer Center are working together on trials of new medications and therapies. This research takes new knowledge about the molecular biology and biochemistry of cancer cells, and their response to potential therapies, from the lab bench to the bedside as soon as possible.

Our Facilities

Our Pediatric Blood and Marrow Transplant Unit is a 28-bed unit that is integrated into the Pediatric Hematology-Oncology Unit at Johns Hopkins All Children’s Hospital.

Our outpatient clinic is located in the Outpatient Care Center directly across the street from our hospital and includes a separate registration area for patients with weakened immune systems. Blood work can be done in the outpatient clinic, and diagnostic imaging services are available across the street in the hospital.

Program History

Our program was founded in 1985 by Robert Good, M.D., Ph.D., a pioneer in the fields of transplantation and immunology. Dr. Good performed the first successful bone marrow transplant that didn’t involve identical twins in 1967 at the University of Minnesota.

Since that first procedure, more than 100,000 blood and bone marrow transplants have been performed worldwide, and promising new methods of stem cell transplantation are being developed.

Questions? Give us a call

We know that you want the best possible care for your child. Our team is happy to assist you with your questions.

Make an appointment online

 We're ready to work with you to explain your options and discuss the best treatment plan for your child.

Prepare for your stay by reading our Inpatient Family Guide

It’s a little easier when you know what to expect and understand what’s going on around you. We hope this guide will be a handy source of information about how our hospital works.

Read more:

Dr. Benjamin Oshrine Connects with Cancer Patients

Dr. Benjamin Oshrine finds inspiration in the connections he makes with patients and families as Division Chief of the hospital’s blood and marrow transplantation program.

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More Than a Toy

A young cancer patient and his sister deliver a bounty of toys to brighten the spirits of children who have to be in the hospital over the holidays.

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Brothers with Life-Threatening Genetic Disease now Thriving

Brothers Jerrick, 5, and Evian, 2, were diagnosed with the same rare, life-threatening genetic immunodeficiency. They received bone marrow transplants at Johns Hopkins All Children’s, and are now back to being healthy, energetic kids. The physicians who have treated them are also researching the disease to continue to advance treatments for future patients.

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Through Teamwork, Sickle Cell Disease Strikes Out

Joao is thriving after a bone marrow transplant to treat his sickle cell disease.

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The Gift

A family seeks hope this holiday season as a little sister gives her brother a special gift.

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