Center for Adoptive Cellular Therapy

Active Clinical Trials and Research Studies

The following are the active clinical trials currently available or anticipated in the Center for Adoptive Cellular Therappy.

Open CAR T-cell Clinical Trials

AALL1721 (CASSIOPEIA): A Phase 2 Trial of tisagenlecleucel in first-line high-risk pediatric and young adult patients with B-ALL who are minimal residual disease (MRD) positive at the end of consolidation (EOC) therapy. This trial is sponsored by Novartis.

Upcoming CAR T-cell Clinical Trials

JCAR017 BCM004: A Phase 1/2, open-label, single arm, multicohort, multicenter trial to evaluate the safety and efficacy of JCAR017 in pediatric subjects with relapsed/refractory B-ALL and B-NHL. This trial is sponsored by Bristol-Myers Squibb